| Meno: | Andrej
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| Priezvisko: | Korman
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| Názov: | Data Structures for Selective Sequencing
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| Vedúci: | doc. Mgr. Tomáą Vinař, PhD.
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| Rok: | 2020
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| Kµúčové slová: | selective sequencing, MinION
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| Abstrakt: | Selective sequencing is very useful technology enabled by the MinION sequencer that
allows us to choose DNA molecules that we want to sequence on-the-fly. In some
scenarios, this can make the whole process of the DNA sequencing much more effective.
However, currently there is no solution that would be able to use the full potential of
this technology for the big reference sequences. The base-calling process is still not fast
enough to satisfy the needs of this method. In this work, we try to build a discretization
algorithm to allow easier work with the raw squiggles. Then we look at the properties
of this representation and discuss its suitability to help achieve the goal of the selective
sequencing.
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