| Meno: | Eduard
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| Priezvisko: | Batmendijn
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| Názov: | Detection of Tandem Repeats in Nanopore Data
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| Vedúci: | doc. Mgr. Tomáą Vinař, PhD.
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| Rok: | 2020
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| Kµúčové slová: | nanopore sequencing, tandem repeats, MinION
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| Abstrakt: | In some applications of DNA sequencing it is desirable to detect repetitive sequences in in-
dividual reads. Standard methods for tandem repeat detection are not suitable for nanopore
reads, due to the high amount of errors contained in the reads. We propose two methods for
detection of tandem repeats directly in the signal from the MinION sequencer, thus avoiding
the need for the inaccurate basecalling step. While our methods do not convincingly out-
perform the baseline approach of detecting repeats on the basecalled sequence, one of them
seems to perform well on sequences that contain repeats of relatively long periods.
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